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Furthermore, they found that, compared with nicotinamide riboside (NR) or NMN, NRH significantly surpassed their effects by causing increases in NAD + concentrations of three to ten times in a broad range of mammalian cells cultures

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[DOI] [PubMed] [Google Scholar] 64.Simoes G.F., Benitez S.U., Oliveira A.L

Currently, there are ten classes of orally available pharmacological agents to treat T2DM: 1) sulfonylureas, 2) meglitinides, 3) metformin (a biguanide), 4) thiazolidinediones (TZDs), 5) alpha glucosidase inhibitors, 6) dipeptidyl peptidase IV (DPP-4) inhibitors, 7) bile acid sequestrants, 8) dopamine agonists, 9) sodium-glucose transport protein 2 (SGLT2) inhibitors and 10) oral glucagon like peptide 1 (GLP-1) receptor agonists